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OXIPASSIVE®

OVULATION INDUCTION SUPPORT

In Women with PCOS

Restoring Glutathione.Restoring Follicular Health.

Where Successful Ovulation Begins.

Large ovarian follicle with a glowing oocyte at its centre

  • Follicular Microenvironment

  • Oocyte Competence

  • Ovulatory Response

Oxipassive® Dual-Precursor Strategy

  1. N-Acetylcysteine

  2. Glycine

  3. Glutathione (GSH)

  4. Healthy Follicular Micro-environment

Pathology & Clinical Management

Understanding the multi-faceted cellular profile of Metabolic PCOS.

Patient Profile

Line illustration of a woman
Diagnosis:
PCOS
Current Treatment:
Letrozole or Clomiphene Citrate
Clinical Findings:
Ovulatory Dysfunction · Poor Follicular Microenvironment

Clinical Summary: Women with PCOS undergoing ovulation induction with suboptimal follicular response and poor ovarian microenvironment.

Oxipassive®

Targeted Co-Treatment for Ovulation Induction Support

  • 2 capsules twice daily
  • For 5 consecutive days
  • Starting from Day 3 of the menstrual cycle
  • Used alongside Letrozole or Clomiphene Citrate
Clipboard with a capsule

Ovarian Pathology in PCOS

Oxidative Stress

Poor Follicular Development

Insulin Resistance

Ovulatory Dysfunction

The Damage Pathway

Intracellular Cascade

  1. ROS

  2. Granulosa Cell Damage

  3. Follicular Impairment

  4. Reduced Ovulatory Response

Oxidative stress disrupts the follicular microenvironment and compromises oocyte quality and ovulation.

The Science of Follicular Protection

How NAC Supports Ovulation Induction

  • Supports granulosa cell survival
  • Reduces oxidative stress during follicular growth
  • Improves ovarian antioxidant defense
  • Creates a healthier follicular microenvironment
  • Supports response to ovulation induction

How Glycine Supports Follicular Health

  • Supports mitochondrial energy production
  • Maintains cellular redox balance
  • Supports granulosa cell metabolism
  • Contributes to healthy follicular physiology

Why Oxipassive During Ovulation Induction

  • Restores endogenous glutathione
  • Protects the follicular microenvironment
  • Supports oocyte maturation
  • Supports healthier ovulatory response
  • Complements Letrozole & Clomiphene Citrate

Art Support Algorithm

Co-Treatment Integration Pathway

PCOS

STANDARD OF CARE

Letrozole / Clomiphene

First-line ovulation induction monotherapy

CO-TREATMENT ADJUVANT

Oxipassive®

Restores master endogenous glutathione pool

TARGET MICROENVIRONMENT

Healthy Follicular Microenvironment

Neutralizes localized ROS, protects granulosa cells, and restores intracellular mitochondrial competence.

CLINICAL OUTCOME

Healthy Ovulation

Facilitates healthy dominant follicle maturation and successful ovulatory response.

Treatment Algorithm

Step-by-Step Protective Cascade

  1. 1. Healthy Environment

    Mitigates intrafollicular oxidative stress

  2. 2. Healthy Granulosa

    Protects surrounding support cells from ROS damage

  3. 3. Oocyte Maturation

    Supports critical mitochondrial competence

  4. 4. Healthy Ovulation

    Supports dominant follicular rupture and release

  5. 5. Pregnancy Potential

    Creates foundations for optimal embryo quality

Clinical Positioning

Ideal as adjunctive antioxidant therapy alongside Letrozole or Clomiphene Citrate during ovulation induction.

  • Ideal as adjunctive antioxidant therapy alongside Letrozole or Clomiphene Citrate during ovulation induction

  • Women with poor ovulatory response

  • Oxidative stress-associated follicular dysfunction

  • Poor follicular microenvironment

Clinical Evidence

Peer-reviewed scientific validation supporting glutathione dual-precursor therapy.